Isoleucine C6H13NO2

Structural Formula

Vander waal Structure

Interactive Image

IUPAC name : Isoleucine
Other names :2-Amino-3-methylpentanoic acid

Essential - Proteogenic - Glycogenic and Ketogenic
Non-Polar, Hydrophobic - Aliphatic

Main Functions:

One of the 3 major Branched-Chain Amino Acids (BCAA), all of which are involved with muscle strength, endurance, and muscle stamina.
Muscle tissue uses Isoleucine as an energy source.
Required in the formation of hemoglobin.
BCAA levels are significantly decreased by insulin.
High dietary sugar or glucose intake causes release of insulin, which, in turn, causes a drop in BCAA levels. Therefore, right before exercise, it is not wise to ingest foods high in glucose or other sugars, as the BCAA's, including Isoleucine will not be readily available to muscles.

Isoleucine Deficiency Seen In:

Panic Disorder
Chronic Fatigue Syndrome (Note: Deficiencies in BCAA in CFS, GWS, FM are associated with muscle weakness, fatigue, and post-exertional exhaustion).
Acute hunger
Kwashiorkor (starvation)

Isoleucine Excess Seen In:

Diabetes Mellitus with ketotic hypoglycemia
Chemical formula C6H13NO2
Molar mass 131.18 g·mol-1
Magnetic susceptibility (χ) -84.9 *106 cm3/mol
Source: Wikipedia