Leucine (C6H13NO2)

Structural Formula

Vander waal Structure

Interactive Image
IUPAC name: Leucine
Other names : 2-Amino-4-methylpentanoic acid

Essential - Proteogenic - Ketogenic - Non-Polar, Hydrophobic - Aliphatic

Main Functions:

As one of the 3 branched-chain amino acids (the other 2 being Isoleucine and Valine), Leucine has all of the properties discussed with Isoleucine, as it pertains specifically to the branched-chain amino acid functions.
Potent stimulator of insulin.
Helps with bone healing.
Helps promote skin healing.
Modulates release of Enkephalins, which are natural pain-reducers.

Leucine Deficiency Seen In:

Chronic Fatigue Syndrome (Note: Deficiencies in BCAA in CFS, GWS, FM are associated with muscle weakness, fatigue, and post-exertional exhaustion).
Acute hunger
Kwashiorkor (starvation)
Vitamin B-12 deficiency in pernicious anemia.

Leucine Excess Seen In:

Chemical formula C6H13NO2
Molar mass 131.18 g·mol-1
Acidity (pKa) 2.36 (carboxyl), 9.60 (amino)
Source: Wikipedia